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The atypical 5-HT(2) receptor mediating tachycardia in pithed rats: pharmacological correlation with the 5-HT(2A) receptor subtype

1. In pithed rats, 5-HT mediates tachycardia both directly (by 5-HT(2) receptors) and indirectly (by a tyramine-like effect). The receptor mediating tachycardia directly has been classified as an ‘atypical' 5-HT(2) receptor since it was ‘weakly' blocked by ketanserin. Moreover, 1-(2,5-dime...

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Detalhes bibliográficos
Main Authors: Centurión, David, Ortiz, Mario I, Saxena, Pramod R, Villalón, Carlos M
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573258/
https://ncbi.nlm.nih.gov/pubmed/11906967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704593
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