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Inhibition of cyclo-oxygenase-2 exacerbates ischaemia-induced acute myocardial dysfunction in the rabbit

1. The effects of treatment with a number of cyclo-oxygenase inhibitors, (celecoxib, meloxicam, DuP-697 and aspirin) on ischaemia-reperfusion-induced myocardial dysfunction were examined using an in vitro perfused rabbit heart model. 2. Ischaemia resulted in myocardial dysfunction, as indicated by a...

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Main Authors: Rossoni, Giuseppe, Muscara, Marcelo N, Cirino, Giuseppe, Wallace, John L
Format: Artigo
Jezik:Inglês
Izdano: 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573250/
https://ncbi.nlm.nih.gov/pubmed/11906968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704585
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