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Glucocorticoids reverse IL-1β-induced impairment of β-adrenoceptor-mediated relaxation and up-regulation of G-protein-coupled receptor kinases
1. The aim of the present study was to examine the effects of glucocorticoid dexamethasone on airway responsiveness to albuterol after intratracheal instillation of saline or IL-1β in Brown-Norway rats in vivo and to elucidate the molecular mechanism of this effect. 2. IL-1β caused a significant red...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573209/ https://ncbi.nlm.nih.gov/pubmed/11861327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704545 |
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