Agmatine, an endogenous ligand at imidazoline binding sites, does not antagonize the clonidine-mediated blood pressure reaction

1. Since agmatine has been identified as a clonidine displacing substance (CDS), the aim of this study was to investigate whether agmatine can mimic CDS-induced cardiovascular reactions in organ bath experiments, pithed spontaneously hypertensive rats (SHR) and anaesthetized SHR. 2. Intravenously-ad...

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Détails bibliographiques
Auteurs principaux: Raasch, Walter, Schäfer, Ulrich, Qadri, Fatimunnisa, Dominiak, Peter
Format: Artigo
Langue:Inglês
Publié: 2002
Sujets:
Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573177/
https://ncbi.nlm.nih.gov/pubmed/11834614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704513
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