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Different glucocorticoids vary in their genomic and non-genomic mechanism of action in A549 cells

1. We have examined the effects of 12 glucocorticoids as inhibitors of A549 cell growth. 2. Other than cortisone and prednisone, all the glucocorticoids inhibited cell growth and this was strongly correlated (r=0.91) with inhibition of prostaglandin (PG)E(2) formation. 3. The molecular mechanism by...

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Detalhes bibliográficos
Main Authors: Croxtall, Jamie D, van Hal, Peter Th W, Choudhury, Qam, Gilroy, Derek W, Flower, Rod J
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573139/
https://ncbi.nlm.nih.gov/pubmed/11815387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704474
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