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Multiple mechanisms of vascular smooth muscle relaxation by the activation of Proteinase-Activated Receptor 2 in mouse mesenteric arterioles

1. Activation of PAR2 in second-order mesenteric arteriole (MA) rings from C57BL/6J, NOS3 (−/−) and PAR2 (−/−) mice was assessed for the contributions of NO, cyclo-oxygenases, guanylyl cyclase, adenylyl cyclase, and of K(+) channel activation to vascular smooth muscle relaxation. 2. PAR2 agonist, SL...

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Detalhes bibliográficos
Main Authors: McGuire, John J, Hollenberg, Morley D, Andrade-Gordon, Patricia, Triggle, Chris R
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573127/
https://ncbi.nlm.nih.gov/pubmed/11786491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704469
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