Activation of endothelial cell IK(Ca) with 1-ethyl-2-benzimidazolinone evokes smooth muscle hyperpolarization in rat isolated mesenteric artery

1. In rat small mesenteric arteries contracted with phenylephrine, 1-ethyl-2-benzimidazolinone (1-EBIO; 3 – 300 μM) evoked concentration-dependent relaxation that, above 100 μM, was associated with smooth muscle hyperpolarization. 2. 1-EBIO-evoked hyperpolarization (maximum 22.1±3.6 mV with 300 μM,...

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Autores principales: Walker, S D, Dora, K A, Ings, N T, Crane, G J, Garland, C J
Formato: Artigo
Lenguaje:Inglês
Publicado: 2001
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Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573096/
https://ncbi.nlm.nih.gov/pubmed/11724762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704415
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