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Evidence of P-glycoprotein mediated apical to basolateral transport of flunisolide in human broncho-tracheal epithelial cells (Calu-3)

1. Transepithelial transport of flunisolide was studied in reconstituted cell monolayers of Calu-3, LLC-PK1 and the MDR1-P-glycoprotein transfected LLC-MDR1 cells. 2. Flunisolide transport was polarized in the apical (ap) to basolateral (bl) direction in Calu-3 cells and was demonstrated to be ATP-d...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Florea, Bogdan I, van der Sandt, Inez C J, Schrier, S Mariette, Kooiman, Klazina, Deryckere, Koen, de Boer, Albertus G, Junginger, Hans E, Borchard, Gerrit
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2001
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573081/
https://ncbi.nlm.nih.gov/pubmed/11724763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704390
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