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Somatostatin release by glutamate in vivo is primarily regulated by AMPA receptors

1. We have used in vivo microdialysis in anaesthetized rats to investigate whether levels of striatal somatostatin (SRIF) can be increased in response to application of the ionotropic glutamate receptor agonists AMPA and NMDA. 2. Application of both AMPA and NMDA (10, 50, 100 and 500 μM) for 20 min...

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Autors principals: Hathway, G J, Humphrey, P P A, Kendrick, K M
Format: Artigo
Idioma:Inglês
Publicat: 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573053/
https://ncbi.nlm.nih.gov/pubmed/11704634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704362
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