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Anandamide-induced relaxation of sheep coronary arteries: the role of the vascular endothelium, arachidonic acid metabolites and potassium channels

1. The effects of the endocannabinoid, anandamide, and its metabolically stable analogue, methanandamide, on induced tone were examined in sheep coronary artery rings in vitro. 2. In endothelium-intact rings precontracted to the thromboxane A(2) mimetic, U46619, anandamide (0.01 – 30 μM) induced slo...

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Autors principals: Grainger, J, Boachie-Ansah, G
Format: Artigo
Idioma:Inglês
Publicat: 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573033/
https://ncbi.nlm.nih.gov/pubmed/11682448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704340
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