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Effects of inhibition of PDE4 and TNF-α on local and remote injuries following ischaemia and reperfusion injury

1. The effects of phosphodiesterase (PDE)4 and TNF-α inhibition were assessed on the local and remote injuries following intestinal ischaemia and reperfusion (I/R) injury in rats. 2. The PDE4 inhibitor rolipram dose-dependently (1 – 10 mg kg(−1)) suppressed the local (intestine) and remote (lung) in...

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Detalhes bibliográficos
Main Authors: Souza, Danielle G, Cassali, Geovanni D, Poole, Steve, Teixeira, Mauro M
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573029/
https://ncbi.nlm.nih.gov/pubmed/11682446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704336
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