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Common mechanisms of inhibition for the Na(+)/glucose (hSGLT1) and Na(+)/Cl(−)/GABA (hGAT1) cotransporters

1. Electrophysiological methods were used to investigate the interaction of inhibitors with the human Na(+)/glucose (hSGLT1) and Na(+)/Cl(−)/GABA (hGAT1) cotransporters. Inhibitor constants were estimated from both inhibition of substrate-dependent current and inhibitor-induced changes in cotranspor...

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Detalhes bibliográficos
Main Authors: Hirayama, Bruce A, Díez-Sampedro, Ana, Wright, Ernest M
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572974/
https://ncbi.nlm.nih.gov/pubmed/11588102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704274
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