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Suppression of K(+)-induced hyperpolarization by phenylephrine in rat mesenteric artery: relevance to studies of endothelium-derived hyperpolarizing factor

In intact mesenteric arteries, increasing [K(+)](o) by 5 mM hyperpolarized both endothelial and smooth muscle cells. Subsequent exposure to 10 μM phenylephrine depolarized both cell types which were then repolarized by a 5 mM increase in [K(+)](o). In endothelium-denuded vessels, increasing [K(+)](o...

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Detalhes bibliográficos
Main Authors: Richards, G R, Weston, A H, Burnham, M P, Félétou, M, Vanhoutte, P M, Edwards, G
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572938/
https://ncbi.nlm.nih.gov/pubmed/11522590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704256
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