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A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus

1. In the absence of indomethacin, anandamide did not contract the guinea-pig bronchus at concentrations up to 100 μM. In the presence of indomethacin (10 μM), anandamide induced concentration-related contractions with a pEC(50) value of 5.18±0.11. It was significantly less potent than capsaicin (pE...

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Detalhes bibliográficos
Main Authors: Craib, Susan J, Ellington, Heather C, Pertwee, Roger G, Ross, Ruth A
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572923/
https://ncbi.nlm.nih.gov/pubmed/11522594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704223
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