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A novel tachykinin NK2 receptor antagonist prevents motility-stimulating effects of neurokinin A in small intestine

1. MEN 11420 (nepadutant) is a potent, selective and competitive antagonist of tachykinin NK2 receptors. 2. The objective of the present study was to assess the capability of the drug to antagonize the stimulatory effects of neurokinin A (NKA) on gastrointestinal motility, as well as to change the f...

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Detalhes bibliográficos
Main Authors: Lördal, Mikael, Navalesi, Giovanni, Theodorsson, Elvar, Maggi, Carlo A, Hellström, Per M
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572917/
https://ncbi.nlm.nih.gov/pubmed/11522614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704217
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