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Analgesic activity of a novel use-dependent sodium channel blocker, crobenetine, in mono-arthritic rats
1. Although sodium channel blockers are effective analgesics in neuropathic pain, their effectiveness in inflammatory pain has been little studied. Sodium channels are substantially up-regulated in inflamed tissue, which suggests they play a role in maintenance of chronic inflammatory pain. We have...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572907/ https://ncbi.nlm.nih.gov/pubmed/11739251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704428 |
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