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Relaxation to authentic nitric oxide and SIN-1 in rat isolated mesenteric arteries: variable role for smooth muscle hyperpolarization

1. Authentic nitric oxide (NO; 0.1–10 μmoles) caused transient, dose-dependent relaxation of phenylephrine-induced tone without changing membrane potential in mesenteric arteries. Larger doses, above 10 μmoles, did not evoke more relaxation (maximal relaxation to 150 μmoles NO in denuded arteries, 6...

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Autori principali: Plane, Frances, Sampson, Laura J, Smith, Jennifer J, Garland, Christopher J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572835/
https://ncbi.nlm.nih.gov/pubmed/11429390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704127
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