Effects of YM471, a nonpeptide AVP V(1A) and V(2) receptor antagonist, on human AVP receptor subtypes expressed in CHO cells and oxytocin receptors in human uterine smooth muscle cells

1. YM471, (Z)-4′-{4,4-difluoro-5-[2-(4-dimethylaminopiperidino)-2-oxoethylidene]-2,3,4,5-tetrahydro-1H-1-benzoazepine-1-carbonyl}-2-phenylbenzanilide monohydrochloride, is a newly synthesized potent vasopressin (AVP) receptor antagonist. Its effects on binding to and signal transduction by cloned hu...

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Autori principali: Tsukada, Junko, Tahara, Atsuo, Tomura, Yuichi, Wada, Koh-ichi, Kusayama, Toshiyuki, Ishii, Noe, Yatsu, Takeyuki, Uchida, Wataru, Taniguchi, Nobuaki, Tanaka, Akihiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572831/
https://ncbi.nlm.nih.gov/pubmed/11429400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704117
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