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Y-27632, an inhibitor of Rho-kinase, antagonizes noradrenergic contractions in the rabbit and human penile corpus cavernosum

We have examined the effect of an inhibitor of Rho-kinase, (+)-(R)-trans-4-(1-aminoethyl)-N-(4-pyridyl) cyclohexanecarboxamide dihydrochloride monohydrate (Y-27632), on the contractions elicited by noradrenergic nerve stimulation and by phenylephrine in the human and rabbit penile corpus cavernosum....

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Detalhes bibliográficos
Main Authors: Rees, Rowland W, Ralph, David J, Royle, Michael, Moncada, Salvador, Cellek, Selim
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572821/
https://ncbi.nlm.nih.gov/pubmed/11399661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704124
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