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[(125)I]-S36057: a new and highly potent radioligand for the melanin-concentrating hormone receptor

1. Shortened, more stable and weakly hydrophobic analogues of melanin-concentrating hormone (MCH) were searched as candidates for radioiodination. Starting from the dodecapeptide MCH(6 – 17), we found that: (1) substitution of Tyr(13) by a Phe residue; (2) addition of a 3-iodo-Tyr residue at the N-t...

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Detalhes bibliográficos
Main Authors: Audinot, Valérie, Lahaye, Chantal, Suply, Thomas, Beauverger, Philippe, Rodriguez, Marianne, Galizzi, Jean-Pierre, Fauchère, Jean-Luc, Boutin, Jean A
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572795/
https://ncbi.nlm.nih.gov/pubmed/11375253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704085
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