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Mechanisms of leukotriene D(4)-induced constriction in human small bronchioles

1. We examined the mechanisms underlying leukotriene D(4)- (LTD(4)) induced constriction of human small (300 – 500 μm i.d.) bronchioles, and the effect of LTD(4) on ion currents and Ca(2+) transients in smooth muscle cells (SMC) isolated from these bronchioles. 2. LTD(4) caused a concentration-depen...

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Detalhes bibliográficos
Main Authors: Snetkov, V A, Hapgood, K J, McVicker, C G, Lee, T H, Ward, J P T
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572783/
https://ncbi.nlm.nih.gov/pubmed/11350860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704076
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