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Agonist and antagonist activities on human NPFF(2) receptors of the NPY ligands GR231118 and BIBP3226

Neuropeptide FF (NPFF) is a part of a neurotransmitter system acting as a modulator of endogenous opioid functions. At this time, no non-peptide or peptide NPFF-antagonists have been discovered. Here, we demonstrate that Neuropeptide Y (NPY) ligands, in fact possess significant ability to interact w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mollereau, Catherine, Gouardères, Christine, Dumont, Yvan, Kotani, Masato, Detheux, Michel, Doods, Henri, Parmentier, Marc, Quirion, Rémi, Zajac, Jean-Marie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572765/
https://ncbi.nlm.nih.gov/pubmed/11325787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704049
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