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Novel histamine H(3)-receptor antagonists and partial agonists with a non-aminergic structure

1. We determined the affinities of eight novel histamine H(3)-receptor ligands (ethers and carbamates) for H(3)-receptor binding sites and their agonistic/antagonistic effects in two functional H(3)-receptor models. The compounds differ from histamine in that the ethylamine chain is replaced by a pr...

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Bibliografiske detaljer
Main Authors: Nickel, Tobias, Bauer, Ulrich, Schlicker, Eberhard, Kathmann, Markus, Göthert, Manfred, Sasse, Astrid, Stark, Holger, Schunack, Walter
Format: Artigo
Sprog:Inglês
Udgivet: 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572731/
https://ncbi.nlm.nih.gov/pubmed/11309237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704013
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