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Characterization of β(1)-selectivity, adrenoceptor-G(s)-protein interaction and inverse agonism of nebivolol in human myocardium

1. Intrinsic activity and β(1)-selectivity are important features of β-blockers in the treatment of patients with coronary syndromes and heart failure. In human myocardium, intrinsic activity and β(1)-selectivity of the novel β-adrenoceptor antagonist nebivolol have not yet been determined. 2. The s...

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Detalhes bibliográficos
Main Authors: Maack, C, Tyroller, S, Schnabel, P, Cremers, B, Dabew, E, Südkamp, M, Böhm, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572729/
https://ncbi.nlm.nih.gov/pubmed/11309254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703992
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