Tedisamil and dofetilide-induced torsades de pointes, rate and potassium dependence

1. Tedisamil is a bradycardiac agent that prolongs the QT interval of the ECG and prevents cardiac arrhythmias. Given this profile, tedisamil might be expected to have proarrhythmic actions similar to Class III antiarrhythmic drugs. To address this question, the actions of dofetilide and tedisamil w...

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Bibliografske podrobnosti
Main Authors: Barrett, Terrance D, Hennan, James K, Fischbach, Peter S, O'Neill, Brian P, Driscoll, Edward M, Lucchesi, Benedict R
Format: Artigo
Jezik:Inglês
Izdano: 2001
Teme:
Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572702/
https://ncbi.nlm.nih.gov/pubmed/11264243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703967
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