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G(q/11) and G(i/o) activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtype

1. Profiles of G protein activation have been assessed using a [(35)S]-GTPγS binding/immunoprecipitation strategy in Chinese hamster ovary cells expressing either M(1), M(2), M(3) or M(4) muscarinic acetylcholine (mACh) receptor subtypes, where expression levels of M(1) and M(3), or M(2) and M(4) re...

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Autors principals: Akam, Elizabeth C, Challiss, R A John, Nahorski, Stefan R
Format: Artigo
Idioma:Inglês
Publicat: 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572629/
https://ncbi.nlm.nih.gov/pubmed/11181437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703892
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