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G(q/11) and G(i/o) activation profiles in CHO cells expressing human muscarinic acetylcholine receptors: dependence on agonist as well as receptor-subtype

1. Profiles of G protein activation have been assessed using a [(35)S]-GTPγS binding/immunoprecipitation strategy in Chinese hamster ovary cells expressing either M(1), M(2), M(3) or M(4) muscarinic acetylcholine (mACh) receptor subtypes, where expression levels of M(1) and M(3), or M(2) and M(4) re...

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Detalhes bibliográficos
Main Authors: Akam, Elizabeth C, Challiss, R A John, Nahorski, Stefan R
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572629/
https://ncbi.nlm.nih.gov/pubmed/11181437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703892
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