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A novel activation of Ca(2+)-activated Cl(−) channel in Xenopus oocytes by Ginseng saponins: evidence for the involvement of phospholipase C and intracellular Ca(2+) mobilization

1. The signal transduction mechanism of ginsenosides, the active ingredients of ginseng, was studied in Xenopus oocytes using two-electrode voltage-clamp technique. Ginseng total saponin (GTS), i.e., an unfractionated mixture of ginsenosides produced a large outward current at membrane potentials mo...

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Detalhes bibliográficos
Main Authors: Choi, Seok, Rho, Seong-Hwan, Jung, Se-Yeon, Kim, Seok-Chang, Park, Chul-Seung, Nah, Seung-Yeol
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572600/
https://ncbi.nlm.nih.gov/pubmed/11159716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703856
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