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Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B

1. Rasagiline [N-propargyl-1R(+)-aminoindan], was examined for its monoamine oxidase (MAO) A and B inhibitor activities in rats together with its S(−)-enantiomer (TVP 1022) and the racemic compound (AGN-1135) and compared to selegiline (1-deprenyl). The tissues that were studied for MAO inhibition w...

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Autori principali: Youdim, Moussa B H, Gross, Aviva, Finberg, John P M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572573/
https://ncbi.nlm.nih.gov/pubmed/11159700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703826
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