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Nitric oxide-mediated modulation of the endothelin-1 signalling pathway in the human cardiovascular system
1. We studied the ability of nitric oxide (NO) to physiologically antagonize endothelin-1 (ET-1) induced constrictions in human internal mammary artery (IMA). We also investigated the hypothesis that NO interacts directly with ET-receptor binding in human heart and aorta. 2. ET-1 potently contracted...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572564/ https://ncbi.nlm.nih.gov/pubmed/11156580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703834 |
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