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Nitric oxide-mediated modulation of the endothelin-1 signalling pathway in the human cardiovascular system

1. We studied the ability of nitric oxide (NO) to physiologically antagonize endothelin-1 (ET-1) induced constrictions in human internal mammary artery (IMA). We also investigated the hypothesis that NO interacts directly with ET-receptor binding in human heart and aorta. 2. ET-1 potently contracted...

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Détails bibliographiques
Auteurs principaux: Wiley, Katherine E, Davenport, Anthony P
Format: Artigo
Langue:Inglês
Publié: 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572564/
https://ncbi.nlm.nih.gov/pubmed/11156580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703834
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