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Inhibition of endotoxin-induced vascular hyporeactivity by 4-amino-tetrahydrobiopterin

1. The 4-amino analogue of tetrahydrobiopterin (4-ABH(4)) is a potent pterin-site inhibitor of nitric oxide synthases (NOS). Although 4-ABH(4) does not exhibit selectivity between purified NOS isoforms, a pronounced selectivity of the drug towards inducible NOS (iNOS) is apparent in intact cells. Th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gibraeil, Hanan D, Dittrich, Peter, Saleh, Samira, Mayer, Bernd
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572510/
https://ncbi.nlm.nih.gov/pubmed/11139456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703752
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