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Suppression of adjuvant arthritis of rats by a novel matrix metalloproteinase-inhibitor

1. BAY 12-9566 (4-[4-(chlorophenyl)phenyl]-4-oxo-2S-(phenylthiomethyl) butanoic acid) is a newly developed, synthetic matrix metalloproteinase (MMP) inhibitor (MMPI) that selectively inhibits MMP-2, MMP-3 and MMP-9 isozymes. We study the effect of BAY 12-9566 on inflammation and cartilage destructio...

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Detalhes bibliográficos
Main Authors: Hamada, Tetsuo, Arima, Nobuyuki, Shindo, Miki, Sugama, Kazushige, Sasaguri, Yasuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572509/
https://ncbi.nlm.nih.gov/pubmed/11139426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703751
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