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Effects of volatile solvents on recombinant N-methyl-D-aspartate receptors expressed in Xenopus oocytes

1. We have previously shown that toluene dose-dependently inhibits recombinant N-methyl-D-aspartate (NMDA) receptors at micromolar concentrations. This inhibition was rapid, almost complete and reversible. The NR1/2B combination was the most sensitive receptor subtype tested with an IC(50) value for...

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Detalhes bibliográficos
Main Authors: Cruz, Silvia L, Balster, Robert L, Woodward, John J
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572451/
https://ncbi.nlm.nih.gov/pubmed/11090101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703666
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