Evidence that PAR-1 and PAR-2 mediate prostanoid-dependent contraction in isolated guinea-pig gallbladder

1. We have investigated the ability of protease-activated receptor-1 (PAR-1), PAR-2, PAR-3 and PAR-4 agonists to induce contractile responses in isolated guinea-pig gallbladder. Thrombin, trypsin, mouse PAR-1 activating (SFLLRN-NH(2)) peptide, and mouse PAR-2 activating (SLIGRL-NH(2)) and human PAR-...

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Bibliographic Details
Main Authors: Tognetto, Michele, Trevisani, Marcello, Maggiore, Barbara, Navarra, Giuseppe, Turini, Alessandro, Guerrini, Remo, Bunnett, Nigel W, Geppetti, Pierangelo, Harrison, Selena
Format: Artigo
Language:Inglês
Published: 2000
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Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572377/
https://ncbi.nlm.nih.gov/pubmed/11030717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703618
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