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Cyclic GMP-independent relaxation of rat pulmonary artery by spermine NONOate, a diazeniumdiolate nitric oxide donor

1. In rat pulmonary artery pre-contracted with phenylephrine, the mechanisms of relaxation to the nitric oxide (NO) donor, spermine NONOate, were investigated. 2. Responses to spermine NONOate were only partially blocked by the soluble guanylate cyclase inhibitor, ODQ (1H-[1,2,4]Oxadiazolo-[4,3,-a]q...

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Bibliographic Details
Main Authors: Homer, Kerry L, Wanstall, Janet C
Format: Artigo
Language:Inglês
Published: 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572374/
https://ncbi.nlm.nih.gov/pubmed/11030715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703613
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