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Dual modulation by thrombin of the motility of rat oesophageal muscularis mucosae via two distinct protease-activated receptors (PARs): a novel role for PAR-4 as opposed to PAR-1

1. Since protease-activated receptors (PARs) are distributed throughout the gastrointestinal tract, we investigated the role of PARs in modulation of the motility of the rat oesophageal muscularis mucosae. 2. Thrombin produced contraction of segments of the upper and lower part of the smooth muscle....

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Detalhes bibliográficos
Main Authors: Kawabata, Atsufumi, Kuroda, Ryotaro, Kuroki, Naoko, Nishikawa, Hiroyuki, Kawai, Kenzo
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572348/
https://ncbi.nlm.nih.gov/pubmed/11015310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703590
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