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Contractile responses to sumatriptan and ergotamine in the rabbit saphenous vein: effect of selective 5-HT(1F) receptor agonists and PGF(2α)

1. Contractile responses to ergotamine, sumatriptan and the novel 5-HT(1F) receptor agonists, LY334370 and LY344864 were examined using the rabbit saphenous vein. 2. Ergotamine (pEC(50)=8.7±0.06) was 30 fold more potent than 5-hydroxytryptamine (5-HT) (pEC(50)=7.2±0.13) and 300 fold more potent than...

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Autores principales: Cohen, Marlene L, Schenck, Kathryn
Formato: Artigo
Lenguaje:Inglês
Publicado: 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572346/
https://ncbi.nlm.nih.gov/pubmed/11015308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703587
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