Amphotericin B severely affects expression and activity of the endothelial constitutive nitric oxide synthase involving altered mRNA stability

1. The therapeutic use of the antifungal drug amphotericin B (AmB) is limited due to severe side effects like glomerular vasoconstriction and risk of renal failure during AmB administration. As nitric oxide (NO) has substantial functions in renal autoregulation, we have determined the effects of AmB...

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Main Authors: Suschek, Christoph Viktor, Bonmann, Eckhard, Kleinert, Hartmut, Wenzel, Michael, Mahotka, Csaba, Kolb, Hubert, Förstermann, Ulrich, Gerharz, Claus-Dieter, Kolb-Bachofen, Victoria
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
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Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572339/
https://ncbi.nlm.nih.gov/pubmed/11015297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703576
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