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Low doses of 8-OH-DPAT prevent the impairment of spatial learning caused by intrahippocampal scopolamine through 5-HT(1A) receptors in the dorsal raphe

1. We studied the effects of low doses of 8-OH-DPAT, a 5-HT(1A) receptor agonist, on the impairment of spatial learning caused by scopolamine injected into the CA1 region of the dorsal hippocampus of rats performing a two-platform spatial discrimination task. 2. Bilateral injections of 4 μg (in 1 μl...

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Detalhes bibliográficos
Main Authors: Carli, Mirjana, Balducci, Claudia, Samanin, Rosario
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572321/
https://ncbi.nlm.nih.gov/pubmed/10991934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703567
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