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Enhanced reduction of myocardial infarct size by combined ACE inhibition and AT(1)-receptor antagonism

1. The effects of the angiotensin-converting-enzyme inhibitor (ACEI) ramiprilat, the angiotensin II type 1 receptor antagonist (AT(1)A) candesartan, and the combination of both drugs on infarct size (IS) resulting from regional myocardial ischaemia were studied in pigs. 2. Both ACEI and AT(1)A reduc...

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Autors principals: Weidenbach, Roland, Schulz, Rainer, Gres, Petra, Behrends, Matthias, Post, Heiner, Heusch, Gerd
Format: Artigo
Idioma:Inglês
Publicat: 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572300/
https://ncbi.nlm.nih.gov/pubmed/10960080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703544
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