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Inhibitory effect of amiodarone on Na(+)/Ca(2+) exchange current in guinea-pig cardiac myocytes

1. The effect of amiodarone on Na(+)/Ca(2+) exchange current (I(NCX)) was examined in single guinea-pig ventricular myocytes using the whole-cell voltage clamp technique. 2. I(NCX) was recorded by ramp pulses from the holding potential of −60 mV in the presence of 140 mM Na(+) and 2 mM Ca(2+) in the...

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Bibliografiske detaljer
Main Authors: Watanabe, Yasuhide, Kimura, Junko
Format: Artigo
Sprog:Inglês
Udgivet: 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572287/
https://ncbi.nlm.nih.gov/pubmed/10960072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703527
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