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Sulphonylurea drugs reduce hypoxic damage in the isolated perfused rat kidney

1. Sulphonylurea drugs have been shown to protect against hypoxic damage in isolated proximal tubules of the kidney. In the present study we investigated whether these drugs can protect against hypoxic damage in a whole kidney preparation. 2. Tolbutamide (200 μM) and glibenclamide (10 μM) were appli...

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書誌詳細
主要な著者: Engbersen, Richard, Moons, Miek M, Wouterse, Alfons C, Dijkman, Henry B, Kramers, Cees, Smits, Paul, Russel, Frans G M
フォーマット: Artigo
言語:Inglês
出版事項: 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572226/
https://ncbi.nlm.nih.gov/pubmed/10928974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703469
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