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Pharmacological characterization of metabotropic glutamate receptor-mediated high-affinity GTPase activity in rat cerebral cortical membranes

1. Activation of heterotrimeric guanine nucleotide-binding regulatory proteins (G-proteins) functionally coupled to metabotropic glutamate receptors (mGluRs) was assessed by agonist-induced high-affinity GTPase (EC3.6.1.-) activity in rat cerebral cortical membranes. 2. L-Glutamate (1 mM) stimulated...

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Detalhes bibliográficos
Main Authors: Nishi, Nobuyuki, Odagaki, Yuji, Koyama, Tsukasa
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572222/
https://ncbi.nlm.nih.gov/pubmed/10928972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703464
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