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Involvement of central opioid systems in human interferon-α induced immobility in the mouse forced swimming test

1. We investigated the mechanism by which human interferon-α (IFN-α) increases the immobility time in a forced swimming test, an animal model of depression. 2. Central administration of IFN-α (0.05–50 IU per mouse, i.cist.) increased the immobility time in the forced swimming test in mice in a dose-...

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Detalhes bibliográficos
Main Authors: Makino, Mitsuhiro, Kitano, Yutaka, Komiyama, Chika, Hirohashi, Masaaki, Takasuna, Kiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572192/
https://ncbi.nlm.nih.gov/pubmed/10903965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703432
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