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The inhibition of cholera toxin-induced 5-HT release by the 5-HT(3) receptor antagonist, granisetron, in the rat

1. The secretagogue 5-hydroxytryptamine (5-HT) is implicated in the pathophysiology of cholera. 5-HT released from enterochromaffin cells after cholera toxin exposure is thought to activate non-neuronally (5-HT(2) dependent) and neuronally (5-HT(3) dependent) mediated water and electrolyte secretion...

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Autors principals: Turvill, J L, Connor, P, Farthing, M J G
Format: Artigo
Idioma:Inglês
Publicat: 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572170/
https://ncbi.nlm.nih.gov/pubmed/10882387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703414
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