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Multiple action sites of flufenamate on ion transport across the rat distal colon

1. The antisecretory effects of flufenamate in the rat distal colon were investigated with the Ussing-chamber and the patch-clamp method as well as by measurements of the intracellular Ca(2+) concentration using fura-2-loaded isolated crypts. 2. Flufenamate (5•10(−4) mol l(−1)) suppressed the short-...

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Bibliographic Details
Main Authors: Schultheiss, G, Frings, M, Hollingshaus, G, Diener, M
Format: Artigo
Language:Inglês
Published: 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572125/
https://ncbi.nlm.nih.gov/pubmed/10864895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703363
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