High affinity interaction of mibefradil with voltage-gated calcium and sodium channels

1. Mibefradil is a novel Ca(2+) antagonist which blocks both high-voltage activated and low voltage-activated Ca(2+) channels. Although L-type Ca(2+) channel block was demonstrated in functional experiments its molecular interaction with the channel has not yet been studied. We therefore investigate...

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Hlavní autoři: Eller, Philipp, Berjukov, Stanislav, Wanner, Siegmund, Huber, Irene, Hering, Steffen, Knaus, Hans-Günther, Toth, Geza, Kimball, S David, Striessnig, Jörg
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572110/
https://ncbi.nlm.nih.gov/pubmed/10821797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703352
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