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Non-competitive antagonism of amylin on CGRP(1)-receptors in rat coronary small arteries
1. We examined the interaction between rat-amylin and relaxations induced by rat-αCGRP and isoprenaline in rat isolated coronary small arteries. 2. Amylin, 0.1–100 nM, had a concentration dependent non-competitive antagonistic effect on rat-αCGRP-induced responses with an EC(50) of approximately 1 n...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572076/ https://ncbi.nlm.nih.gov/pubmed/10807677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703316 |
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