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Pharmacological evaluation of the role of cyclooxygenase isoenzymes on the micturition reflex following experimental cystitis in rats

1. Prostanoids, generated from cyclooxygenase (COX) isoenzymes, play a role in the physiological function of the lower urinary tract and are important mediators of inflammatory hyperalgesia. The present work evaluates the effects of the COX-1/COX-2 inhibitor dexketoprofen as well as of a selective C...

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Bibliographic Details
Main Authors: Lecci, Alessandro, Birder, Lori A, Meini, Stefania, Catalioto, Rose-Marie, Tramontana, Manuela, Giuliani, Sandro, Criscuoli, Marco, Maggi, Carlo A
Format: Artigo
Language:Inglês
Published: 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572070/
https://ncbi.nlm.nih.gov/pubmed/10807670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703309
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