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The phosphatidylinositol 4-kinase inhibitor phenylarsine oxide blocks evoked neurotransmitter release by reducing calcium entry through N-type calcium channels

1. The effects of the phosphatidylinositol 4-kinase inhibitor, phenylarsine oxide (PAO), on acetylcholine (ACh) release and on prejunctional Ca(2+) currents were studied at the frog neuromuscular junction using electrophysiological recording techniques. 2. Application of PAO (30 μM) increased both s...

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Detalhes bibliográficos
Main Authors: Searl, T J, Silinsky, E M
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572064/
https://ncbi.nlm.nih.gov/pubmed/10807681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703299
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