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Non-NF-κB elements are required for full induction of the rat type II nitric oxide synthase in vascular smooth muscle cells

1. We have investigated the role of the NF-κB binding sites and other promoter elements beyond NF-κB in iNOS induction in rat vascular smooth muscle cells (SMC). 2. Rat aortic SMC transfected with iNOS promoter constructs with either mutation or deletion of the downstream NF-κB site exhibited about...

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Detalhes bibliográficos
Main Authors: Zhang, Hanfang, Teng, Xingwu, Snead, Connie, Catravas, John D
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572057/
https://ncbi.nlm.nih.gov/pubmed/10807663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703284
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